主要以国家生物安全领域关注度极高的BSL-3,BSL-4级或对生命健康造成严重威胁的重要病毒(副黏病毒,布尼亚病毒和甲病毒)为研究对象,围绕关键宿主因子调控病毒复制生命周期的作用机制;病毒感染引起出血热,诱发脑炎和肺炎等疾病的分子机理;以及病毒如何逃逸宿主抗病毒天然免疫等开展原创性的研究。
Zheng, Z.Q.#, Fu, Y.Z. #*, Wang, S.Y., Xu, Z.S., Zou, H.M., and Wang, Y.Y. * Herpes Simplex Virus Protein UL56 Inhibits cGAS-Mediated DNA Sensing to Evade Antiviral Immunity. Cell Insight 2022, (1): 100014.
Zheng, Z.Q.#, Wang, S.Y. #, Xu, Z.S. #, Fu, Y.Z.*, and Wang, Y.Y.* SARS-CoV-2 Nucleocapsid Protein Impairs Stress Granule Formation to Promote Viral Replication. Cell Discovery 2021, 25;7(1):38
Fu, Y.Z. #*, Wang, S.Y. #, Zheng, Z.Q. #, Yi, H., Li, W.W., Xu, Z.S., and Wang, Y.Y*. SARS-CoV-2 Membrane Glycoprotein M Antagonizes the MAVS-Mediated Innate Antiviral Response. Cellular & Molecular Immunology, 2020, 18(3): 613-620.
Zou, H.M., Huang, Z.F., Yang, Y, Luo., W.W., Wang, S.Y., Luo, M.H., Wang, S.Y., Luo, M.H., Fu, Y.Z. *, and Wang, Y.Y.* Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response. J Virol 2020, 94(12).
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