致力于病毒学、纳米技术、合成生物学交叉学科研究，研究兴趣包括：病毒样颗粒等生物纳米材料的可控组装与精准功能化、病毒启发的智能递送系统、新型纳米疫苗、面向病毒学的微纳分析新技术等。
Songxin Guo#, Yi Ru#, Hui Zhang, Junbiao Xue, Huanan Liu, Dong Men, Zongqiang Cui, Chaochao Shen, Hong Tian, Chun Ma, Jun Gong, Jintian Xu, Dianbing Wang, Rui Gong, Xiaowei Zhang, Heng Rong, Yan-Yi Wang, Chenli Liu, Zhuojun Dai, Shengce Tao*, Jiaoyu Deng*, Haixue Zheng*, Feng Li*, Xian-En Zhang*. An African swine fever virus-specific antibody reactome reveals antigens as potential candidates for vaccine development. Journal of Virology. 2025: e00478-25
Wei Zhou, Shaojie Ma, Ruimin Gao, Yufu Tang, Hui Zhang, Ao Liang, Mengsi Yang, Chun Ma, Quli Fan*, Xian-En Zhang*, Feng Li*. Assembly of matryoshka-type protein nanocages for compartmentalized oxygen sensing. Nano Letters. 2025; 25 (11): 4433-4440
Chun Ma, Mengsi Yang, Wei Zhou, Songxin Guo, Hui Zhang, Jun Gong, Xian-En Zhang, Feng Li*. The RNA landscape of in vivo-assembled MS2 virus-like particles as mRNA carriers reveals rna contamination from host viruses. Nano Letters. 2025; 25 (8): 3038–3044.
Mengsi Yang#, Guibo Rao#, Long Li#, Linlin Qi, Chun Ma, Hui Zhang, Jun Gong, Bin Wei, Xian-En Zhang, Guosong Chen*, Sheng Cao* and Feng Li*. Transformation of a viral capsid from nanocages to nanotubes and then to hydrogels: Redirected self-assembly and effects on immunogenicity. ACS Nano. 2024; 18(21): 13755-13767.
Ao Liang, Wei Zhou, Hui Zhang, Juan Zhang, Xian-En Zhang, Ti Fang*, Feng Li*. Effects of individual amino acids on the blood circulation of biosynthetic protein nanocages: toward guidance on surface engineering. Advanced Healthcare Materials. 2023; 12(26): 2300502 (Inside back cover paper)
Ruimin Gao#, Huan Tan#, Shanshan Li#, Shaojie Ma, Yufu Tang, Kaiming Zhang, Zhiping Zhang, Quli Fan, Jun Yang*, Xian-En Zhang*, Feng Li*. A prototype protein nanocage minimized from carboxysomes with gated oxygen permeability. Proceedings of the National Academy of Sciences of the United States of America. 2022; 119 (5): e2104964119
Wenjing Zhang, Qingyan Jia, Yibo Teng, Mengsi Yang, Hui Zhang, Xian-En Zhang, Pengfei Wang, Jiechao Ge*, Sheng Cao*, Feng Li*. An ultrastable virus-like particle with a carbon dot core and expanded sequence plasticity. Small. 2021; 17 (35), 2101717
Chengchen Xu, Weiwei Zhu, Hanjing Mao, Wenjing Zhang, Gen-Quan Yin*, Xian-En Zhang*, Feng Li*. Switch from polymorphic to homogenous self-assembly of virus-like particles of simian virus 40 through double-cysteine substitution. Small. 2020; 16(45): 2004484 (Back cover paper)
Lingling Li, Chengchen Xu, Wenjing Zhang, Francesco Secundo, Chunyan Li, Zhi-Ping Zhang, Xian-En Zhang* and Feng Li*. Cargo-Compatible Encapsulation in Virus-Based Nanoparticles. Nano Letters. 2019; 19(4): 2700-2706
Chunyan Li, Feng Li,* Yejun Zhang, Wenjing Zhang, Xian-En Zhang, and Qiangbin Wang*. Real-Time Monitoring Surface Chemistry-Dependent In Vivo Behaviors of Protein Nanocages via Encapsulating an NIR-II Ag2S Quantum Dot. ACS Nano. 2015; 9(12): 12255-12263
