| 职务 | | 职称 | 研究员 |
学历 | 博士 | 通讯地址 | 湖北省武汉市武昌区小洪山区 44号 |
电话 | 027-87199279 | 邮编 | 430071 |
传真 | 027-87199279 | 电子邮件 | fli@wh.iov.cn |
教育经历
2004.09-2009.07: 中国科学院武汉病毒研究所,微生物学,博士。
2000.09-2004.07:山东大学,生物技术,学士。
工作经历
2013.09 - :中科院武汉病毒研究所,研究员。
2012.01-2013.08:中科院苏州纳米技术与纳米仿生研究所,副研究员。
2009.12-2011.12:中科院苏州纳米技术与纳米仿生研究所,博士后。
2009.07-2009.11:中科院苏州纳米技术与纳米仿生研究所,助理研究员。
学术兼职
研究内容
专注于病毒纳米生物技术研究,研究兴趣包括:蛋白质(病毒样颗粒等)、纳米材料等生物纳米元件的可控组装与功能化;新型生物标志物与探针的发现与设计;基于蛋白质的生物医学影像探针与智能递送载体;功能性蛋白质纳米材料/结构的活体应用——界面效应、精准靶向、疾病诊疗等。
主持项目
国家重点研发计划(课题)、国家自然科学基金面上项目、中科院重点部署项目、中科院院地合作项目、江苏省自然科学基金、中国博士后科学基金等。
成果
论文:
1. ChunyanLi, Feng Li,* Yejun Zhang, Wenjing Zhang, Xian-En Zhang, andQiangbin Wang*. Real-Time Monitoring Surface Chemistry-Dependent InVivo Behaviors of Protein Nanocages via Encapsulating an NIR-II Ag2SQuantum Dot. ACS Nano9: 12255-12263. (2015)
2. LingzhiMa, Feng Li,* Ti Fang, Jianting Zhang, and Qiangbin Wang*. ControlledSelf-Assembly of Proteins into Discrete Nanoarchitectures Templated by GoldNanoparticles via Monovalent Interfacial Engineering. ACS Applied Materials & Interfaces 7(20):11024-11031. (2015)
3. Feng Li and Qiangbin Wang*. Fabrication ofnanoarchitectures templated by virus-based nanoparticles: strategies andapplications. Small 10(2): 230-245. (2014) (Back-coverpaper; invited review)
4. Feng Li#, Huiling Chen#, Lingzhi Ma, Kun Zhou, Zhi-Ping Zhang, ChunMeng*, Xian-En Zhang* and Qiangbin Wang*. Insights into stabilization of aviral protein cage in templating complex nanoarchitectures: roles of disulfidebonds. Small 10(3): 536-543. (2014) (#共同第一作者)
5. Feng Li, Huiling Chen, Yejun Zhang, Zhong Chen, Zhi-PingZhang, Xian-En Zhang* and Qiangbin Wang*. Three-dimensional gold nanoparticleclusters with tunable cores templated by a viral protein scaffold. Small8(24): 3832-3838. (2012)
6. Feng Li, Ding Gao, Xiaomin Zhai, Yanhua Chen, Tao Fu,Dongmin Wu, Zhi-Ping Zhang, Xian-En Zhang* and Qiangbin Wang*. Tunable,discrete, three-dimensional hybrid nanoarchitectures. Angewandte ChemieInternational Edition 123(18): 4288-4291. (2011)
7. Feng Li, Yanhua Chen, Huiling Chen, Wei He, Zhi-PingZhang, Xian-En Zhang* and Qiangbin Wang*. Monofunctionalization of proteinnanocages. Journal of the American Chemical Society 133(50):20040-20043. (2011)
8. Feng Li#, Ke Li#, Zong-Qiang Cui, Zhi-Ping Zhang, Hong-Ping Wei, DingGao, Jiao-Yu Deng and Xian-En Zhang*. Viral coat proteins as flexiblenano-building-blocks for nanoparticle encapsulation. Small 6(20):2301-2308. (2010) (#共同第一作者)
9. Feng Li, Zhi-Ping Zhang, Jun Peng, Zong-Qiang Cui, Dai-WenPang, Ke Li, Hong-Ping Wei, Ya-Feng Zhou, Ji-Kai Wen and Xian-En Zhang*.Imaging viral behavior in mammalian cells with self-assembledcapsid–quantum-dot hybrid particles. Small 5(6): 718-726. (2009)(Inside-cover paper; highlighted by Nature China)
10. Kun Zhou, Feng Li, Gaole Dai, Chun Meng andQiangbin Wang*. Disulfide bond: dramatically enhanced assembly capability andstructural stability of tobacco mosaic virus nanorods. Biomacromolecules14(8): 2593-2600. (2013)
11. Yan Zhang, Yejun Zhang, Guosong Hong, Wei He,Kun Zhou, Kai Yang, Feng Li, Guangcun Chen, Zhuang Liu, Hongjie Dai andQiangbin Wang*. Biodistribution, pharmacokinetics and toxicology of Ag2Snear-infrared quantum dots in mice. Biomaterials 34(14):3639-3646. (2013)
12. Ding Gao, Zhi-Ping Zhang, Feng Li, DongMen, Jiao-Yu Deng, Hong-Ping Wei, Xian-En Zhang* and Zong-Qiang Cui*. Quantumdot-induced viral capsid assembling in dissociation buffer. Internationaljournal of nanomedicine 8: 2119. (2013)
13. Yan Zhang, Guosong Hong, Yejun Zhang, GuangcunChen, Feng Li, Hongjie Dai* and Qiangbin Wang*. Ag2S quantumdot: A bright and biocompatible fluorescent nanoprobe in the secondnear-infrared window. ACS Nano 6(5): 3695-3702. (2012)
14. Tingjuan Wang, Zhi-ping Zhang, Ding Gao, FengLi, Hong-ping Wei, Xiaosheng Liang, Zong-qiang Cui* and Xian-En Zhang*.Encapsulation of gold nanoparticles by simian virus 40 capsids. Nanoscale3(10): 4275-4282. (2011)
15. Yaping Du, Bing Xu, Tao Fu, Miao Cai, Feng Li,Yan Zhang and Qiangbin Wang*. Near-infrared photoluminescent Ag2Squantum dots from a single source precursor. Journal of the AmericanChemical Society 132(5): 1470-1471. (2010)
16. Miao Cai, Feng Li, Yan Zhang and QiangbinWang*. One-pot polymerase chain reaction with gold nanoparticles for rapid andultrasensitive DNA detection. Nano Research 3(8): 557-563. (2010)
17. 李峰, 董博华, 张叶俊, 兰祥, 李春炎, 王强斌*. 无机半导体纳米晶光学性质的设计、调控及其生物医学应用. 中国科学:化学. 44(2):180-190. (2014)
专利:
1. 王强斌,李峰,陈艳华。不对称病毒纳米颗粒的制备方法,授权公告日:2014-04-16。
2. 乐加昌,陶宁,张先恩,李峰。纳米生物机器人及其应用,授权公告日:2012-09-05。
奖励
2015年:张先恩、张治平、李峰、王殿冰、门冬。湖北省自然科学一等奖。
2015年:李峰。“黄鹤英才科技计划”。
2015年:李峰。ChinaNanomedicine2015 Best Poster Award。
2010年:李峰。湖北省优秀博士学位论文。